Schizophrenia Is A Heterogeneous Illness - 1719 Words

Schizophrenia is a heterogeneous illness that may involve several pathophysiological gender differences. For men and women incidence risk peaks between 20-29 years of age, and women also have a second risk peak between 30–39 years of age. Negative symptoms including low motivation and withdrawal are more frequent in men and appear up to six years before diagnosis (Hafner, 2005; Hafner et al., 1993; Morgan et al., 2008). Women exhibit greater levels of depression and positive symptoms including sexual inappropriateness, impulsivity and delusions (Mendrek et al., 2015; Van der Werf et al., 2014). Sex differences in either age of onset or prevalence of negative symptoms are not as evident in patients that have a family history of schizophrenia (Bergen et al., 2014; Hafner et al., 1998). Estrogen has been proposed to have a possible protective role that may account for a later age of disease onset in women, when levels are lowest during post-response rates to antipsychotic drugs are also higher in women menopause (Allen et al., 2013; Hafner, 2005; Leung M.D. Chue M. R. C. Psych., 2000; Ochoa et al., 2012). Obstetric complications have also been connected with an increased risk of developing schizophrenia, an earlier age of disease onset, poorer outcomes and ventricular enlargement. Such complications appear to be more frequent and severe in males than females. (Allen et al., 2013; Dalman et al., 1999; Kelly et al., 2004). Prenatal exposure to influenza 5 months before birthShow MoreRelatedSchizophreni A Mental Illness1199 Words   |  5 PagesChidubem Ike-Asogwa Professor Crawley PSYCH 201 April 17, 2017 Schizophrenia continues to create new challenges today and continue to be a complicated mental illness. 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